Dyah Ariani Perwitasari


A  Cancer  patients  need  long  term  therapy  in  the  treatment of their disease. One of the outcome of cancer treatment in patients of  quality  of  life.  Because  of  the  limited  instrument  for  measuring cancer patients’ quality of life in Indonesian version, thus this study is  aimed  to  develop  the  validation  of  Indonesian  version  of  Short Form-36  questionnaire  in  cancer  patients.  The  observational  study was  carried  out  in  this  study.  Data  were  collected  from  cancer patients  in  the  Oncology  Department  of   Sardjito  Hospital, Yogyakarta,  Indonesia,  who  were  treated  with  cisplatin  at  the dosage  of  ≥  50mg/m2 as  monotherapy  or  in  combinations.  The validation  process  involved  known-group  validity,  discriminant validity, convergent validity and factor analysis. About 203 subjects who  were  diagnosed  with  cancer  were  recruited  in  this  study.  The

known-group  validity  test  showed  that  there  were  no  significant differences  of  SF-36  domains  among  different  diagnosa.  All  of  the questions  met  the  criteria  of  convergent  validity  except  for  the questions  number  26,  28,  30  and  32.  Furthermore,  the  questions number 2  and  28  did  not meet  the  criteria  of discriminant  validity. This  study  presents  that  many  questions  are  needed  to  be reconstructed,  due  to  the  result  of  factor  analysis  which  showed that  those  questions  are  loaded  significantly  with  other  domain’s questions.  The  development  of  Indonesian  version  of  SF-36  scales in cancer disease is still less unstatisfactory. According to the result of this study, future study with new construction of questions in this version is still necessary.

Key words: validation, SF-36, Indonesia, cancer


Full Text:



Awad, M. A., Denic, S., & El, T. H. (2008). Validation of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaires for Arabic-speaking Populations. Ann. N. Y. Acad. Sci. 1138, 146-154, doi:NYAS1 138021 [pii];10.1196/annals.1414.021.

Chase, D. M., Wenzel, L. B., & Monk, B. J. (2012). Quality-of-life results used to endorse changes in standard of care for recurrent platinum-sensitive ovarian cancer. Expert. Rev. Pharmacoecon. Outcomes. Res. 12, 279-281, doi:10.1586/erp.12.22.

Fredheim, O. M., Borchgrevink, P. C., Saltnes, T., & Kaasa, S. (2007). Validation and comparison of the health-related qualityof-life instruments EORTC QLQ-C30 and SF-36 in assessment of patients with chronic nonmalignant pain. J. Pain Symptom. Manage. 34, 657-665, doi:S0885-3924(07)00422-8 [pii];10.1016/j.jpainsymman.2007.01.011.

Gale, N., Enright, S., Reagon, C., Lewis, I., & van, D. R. (2012). A pilot investigation of quality of life and lung function following choral singing in cancer survivors and their carers. Ecancermedicalscience. 6, 261, doi:10.3332/ecancer.2012. 261 [doi];can-6-261 [pii].

Hoopman, R., Terwee, C. B., Deville, W., Knol, D. L., & Aaronson, N. K. (2009). Evaluation of the psychometric properties of the SF-36 health survey for use among Turkish and Moroccan ethnic minority populations in the Netherlands. Qual. Life Res. 18, 753-764, doi:10.1007/s11136-009-9491-1.

Li, L., Wang, H. M., & Shen, Y. (2003). Chinese SF-36 Health Survey: translation, cultural adaptation, validation, and normalisation. J. Epidemiol. Com. Health 57, 259-263.

McPherson, A. & Martin, C. R. (2012). A review of the measurement properties of the 36-item short-form health survey (SF-36) to determine its suitability for use in an alcohol-dependent population. J. Psychiatr. Ment. Health Nurs., doi:10.1111/j.1365-2850.2012.01896.x.

Perwitasari, D. A., Atthobari, J., Dwiprahasto, I., Hakimi, M., Gelderblom, H., Putter, H., Nortier, J. W., Guchelaar, H. J., & Kaptein, A. A. (2011). Translation and validation of EORTC QLQ-C30 into Indonesian version for cancer patients in Indonesia. Jpn. J. Clin. Oncol. 41, 519-529, doi:hyq243 [pii];10.1093/jjco/hyq24.

Perwitasari, D. A., Atthobari, J., Mustofa, M., Dwiprahasto, I., Hakimi, M., Gelderblom, H., Putter, H., Nortier, J. W., Guchelaar, H. J., & Kaptein, A. A. (2012). Impact of chemotherapy-induced nausea and vomiting on quality of life in indonesian patients with gynecologic cancer. Int. J. Gynecol. Cancer 22, 139-145, doi:10.1097/IGC.0b013e318234f9ee.

Scarpa, M., Valente, S., Alfieri, R., Cagol, M., Diamantis, G., Ancona, E., & Castoro, C. (2011). Systematic review of healthrelated quality of life after esophagectomy for esophageal cancer.

World J. Gastroenterol. 17, 4660-4674, doi:10.3748/wjg.v17.i42.4660.

Sussman, N. (1995). Reactions of patients to the diagnosis and treatment of cancer. Anticancer Drugs 6 Suppl 1, 4-8.

Xie, Y., Zhao, F. H., Lv, S. H., Huang, H., Pan, X. F., Yang, C. X., & Qiao, Y. L. (2012). Assessment of quality of life for patients with different clinical stage cervical cancer. Chin J. Cancer, doi:cjc.012.10047 [pii];10.5732/cjc.012.10047



  • There are currently no refbacks.


Creative Commons License
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Indonesian J Pharm indexed by:

analytics View My Stats