Anti-inflammatory  activity  of  dominant  compound  of  mahkota dewa fruit Phaleria macrocarpa Scheff. Boerl

Ria Mariani; Komar Ruslan Wirasutisna; As’ari Nawawi; I Ketut Adnyana

doi:10.14499/indonesianjpharm0iss0pp129-133

Anti-inflammatory activity of dominant compound of mahkota dewa fruit Phaleria macrocarpa Scheff. Boerl

Ria Mariani, Komar Ruslan Wirasutisna, As’ari Nawawi, I Ketut Adnyana

Abstract

The anti-inflammatory effectof dominant compound of mahkota dewa fruit (Phaleria macrocarpaScheff. Boerl), a hydroxyl benzophenon glucoside,to Wistar female rats (using λ-karagenan as inflammatory inducer) has been investigated. The inflammation was measured by pletismometer. The test has been used physiology NaCl solution as a control andNaproxen at a dose of 22.5 mg/kg body weight as a standard. Anti-inflammatorytest was showed that the decreased inflammation of the isolate at a dose of 22.5 mg/kg body has twice lower than the standard.

Key words: Phaleria macrocarpa, anti-inflammatory activity, hydroxyl benzophenon glucoside

Full Text:

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DOI: http://dx.doi.org/10.14499/indonesianjpharm0iss0pp129-133