The effect of pharmacy visit to the potential drug interactions in the hospitalized geriatric patient at Dahlia ward Prof. Dr. Margono Soekarjo hospital

Heny Ekowati, Tunggul Adi P., Trisnowati ., Budi Rahardjo


Pharmaceutical care is the responsible provision of drug therapy for the purpose of achieving definite outcomes that improve a patient’s quality of life. Ward pharmacy is one way to realizing pharmaceutical care. This research’s aim was to study potential drug interactions in geriatric patient hospitalized at Dahlia ward Prof. Dr. Margono Soekarjo hospital, before and after ward pharmacy. The research used before and after study method, comparing potential drug interactions before and after ward pharmacy from March - June 2006. The different significance of drug interactions before and after ward pharmacy tested with Mann-Whitney test. Software which used in statistical analysis was SPSS (Statistical Product Social Science for) version 11.

The study showed that total potential drug interaction before and after ward pharmacy were 3,69% and 5,12%. Drug interactions with significance rating 1, 2, and 3 before ward pharmacy were 0.08 ; 0.16 and 0.04 respectively ; while after ward pharmacy were 0.33 ; 0.14 and 0.09 respectively. The statistical analysis indicate that there was no a significance difference of drug interactions before and  after ward pharmacy (P> 0,05). The result was used to improve the system of pharmaceutical care in RSUD Prof. Dr Margono Soekarjo Purwokerto.

Key words: ward pharmacy, geriatric patient, potential drug interaction


Bedouch, P., Allenet, B., Labarere, J., Brudieu, J., Chen, C., Chevrot, D., Tessir, A., Trivin, C., Rousseau, A., and Calop., J., 2005, Diffusion of Pharmacist Interventions within the Framework of Clinical Pharmacy Activity in the Clinical Ward, Therapie 60 (5): 515-22.

Cipolle, J.R., Strand, L.M., Morley, P.C., 1998, Pharmaceutical Care Practice, McGraw-Hill Health Professions Division, New York.

Fradgley, S.J., 2003, Interaksi Obat, dalam Farmasi Klinis (Clinical Pharmacy) Menuju Pengobatan Rasional dan Penghargaan Pilihan Pasien, editor: Mohamed Aslam, Chik Kaw Tan, Adji Prayitno, Elex Media Komputindo, Jakarta .

ISFI, 2004, Kompetensi Farmasis Indonesia, Badan Pimpinan Pusat Ikatan Sarjana Farmasi Indonesia, Jakarta.

Jeffery, S., Ruby,C.M, Twersky, J., Hanlon, J.T., 1998, Effect of an Interdisciplinary Team on Suboptimal Prescribing in a Long-Term Care Facility, dipresentasikan pada : the American Society of Consultant Pharmacists Annual Meeting, 12 November 1998.

Lam, S., dan Ruby, C.M., 2005, Impact Of An Interdisciplinary Team On Drug Therapy Outcomes In A Geriatric Clinic, Am J Health-Syst Pharm 62:626-9.

Liu, G.G., dan Christensen, D.B., 2002, The Continuing Challenge of Inappropriate Prescribing in The Eldery: An Update of The Evidence, J Am Pharm Assoc 42(6):847-857.

Prest, M., 2003, Penggunaan Obat Pada Lanjut Usia, dalam Farmasi Klinis (Clinical Pharmacy) Menuju Pengobatan Rasional dan Penghargaan Pilihan Pasien, editor: Mohamed Aslam, Chik Kaw Tan, Adji Prayitno, Elex Media Komputindo, Jakarta.

Raharjo, B., 2004, Peningkatan Layanan Kefarmasian Komunitas, disampaikan pada Workshop II Badan Pimpinan Cabang Ikatan Sarjana Farmasi Indonesia, di Rumah Sakit Margono Soekarjo, 28 -29 Mei 2004.

Rahmawati, F., Ikawati, Z., Retnoningtyas, Pramantara, I.D.P., 2005, Drug Related Problems (DRPs) Identification in Geriatric Patient Hospitalized at Bougenvile Ward Dr. Sardjito Hospital Yogyakarta Indonesia, dipresentasikan pada: 6th Asian Conference on Clinical Pharmacy 2006, Rajavithi Hospital, Bangkok, Thailand, 6 – 9 Juli 2006.

Spinewine, A., Dhillon, S., Mallet, L., Tulkens, P.M., Wilmotte, L., and Swine., C., 2006, Implementation of Ward-Based Clinical Pharmacy Services in Belgium, Description of the Impact on a Geriatric Unit, Ann Pharmacother 40 (4): 720-8.

Tatro , 2001, Drug Interaction FactsTM, editor: David S. Tatro, Facts and Comparisons, St. Louis, Missouri.



  • There are currently no refbacks.


Creative Commons License
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Indonesian J Pharm indexed by:

analytics View My Stats