Spectral analysis of aegelin isolated from maja leaves (Aegle marmelos Corr.)

Sugeng Riyanto


Aegelin is an alkaloid which isolated from Maja (Aegle marmelos Corr.) leaves. The molecular structure of the compound contains a chiral carbon atom. In our earlier publications the existence and influence of a chiral carbon atom have not been discussed yet. The existing of the chiral carbon atom gave rise two pair of doublets at d 3.67 J=3.4 Hz and d 3.43 J=8.5 Hz in the proton nmr spectrum. The doublets are signal of two proton which attached on adjacent atom of the chiral carbon atom which is confirmed by
the two dimension nmr spectrum (HMQC). The two protons are magnetic unequivalent which cause their chemical shifts are different. The protons appear as two doublet with different J value because its couple to a proton attached at the chiral carbon atom and the spin-spin splitting is observed. The existence of the two pairs of the doublets at d 3.67 d,J=3.4 Hz and d 3.42 d,J=8.5 Hz because the isolated aegelin from E.marmelos leaves contains of its enantimeer.
Key words: E. marmelos, aegelin, enantiomeer, spectroscopy

Full Text:



Buckingham J., Macdonald F.M., and Bradley H.M., 1994, Dictionary of Natural Products, vol.4, London:Chapman & Hall.Manandhar, M. D., Shoeb, A., Kapil, R.S., and Popli, S.P., 1978, New Alkaloid from Aegle marmelos, Phytochemistry 17:1814-1815.

Pavia Donald L, G. M. Lampman, G. S., and Kris Jr.,1979, Introduction to Spectroscopy, WB. Saunders Company, Philadelpia, p.152-154.

Sharma B. R., Rattan R. K. and Sharma P., 1981, Marmeline, an alkaloid, and other components of unripe fruits of Aegle marmelos, Phytochemistry, 20(11), 2606-2607.

Sugeng Riyanto, Mohd.Aspollah Sukari, Mawardi Rahmani, Abd.Manaf Ali1, Umi Kalsom Yusuf 2, Norio Aimi3 and Mariko Kitajima3 ,2001, Alkaloids from Aegle marmelos (Rutaceae), The Malaysian Journal of Analytical Sciences, Vol.7 No.2, 463-465,

Sugeng Riyanto, 2003, Phytochemical studies and Bioactivity Tests of Murraya Paniculata Jack, Aegle marmelos Correa and Zingiber amaricans Blume, Doctor of Philisophy Thesis, Universiti Putra Malaysia,150-160.

DOI: http://dx.doi.org/10.14499/indonesianjpharm0iss0pp95-100


  • There are currently no refbacks.


Creative Commons License
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Indonesian J Pharm indexed by:

analytics View My Stats