PHYTOCHEMICAL SCREENING AND ANALYSIS POLYPHENOLIC ANTIOXIDANT ACTIVITY OF METHANOLIC EXTRACT OF WHITE DRAGON FRUIT (Hylocereus undatus)
White dragon fruit is a well known and widely used herbal medicine, especially in Asia, which contains several interesting bioactive constituents and possesses health promoting properties. The aim of this study was to analyze for the bioactive compounds, evaluate total phenolic contents and antioxidant capacities of methanolic extract of white dragon fruit. The antioxidant activity was determined by the 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity assay. Total phenolic content were determined by Folin-Ciocalteu method. Phytochemical screening of the white dragon fruit showed the presence of triterpenoid, alkaloid, flavonoid and saponin. The extract exhibited strong antioxidant activity with IC50 of 193 μg/mL, and total phenolic content of 246 μg/mL in 1 Kg dry extract.
Key words: antioxidant activity, total phenolic, DPPH, white dragon fruit
Belsare, D.P., Pal, S.C., Kazi, A.A., Kankate, R.S., and Vanjari, S.S., 2010, Evaluation of Antioxidant Activity of Chalcones and Flavonoids. Int. J. ChemTech. Res., 2(2), 1080-1089.
Egwaikhide, P.A., Okeniyi, S.O., and Gimba, C.E., 2007, Screening for Anti-Microbial Activity and Phytochemical Constituents of some Nigerian Medicinal Plants, Advan. in Biol. Res.1(5-6), 155-158
Ghafar, M.F.A., Prasad, K.N., Weng, K.K., and Ismail, A., 2010, Flavonoid, hesperidine, total phenolic contents and antioxidant activities from Citrus species, African J. Biotech.,9(3), 326-330
Gill, N.S., Bajwa, J., Sharma, P., Dhiman, K., Sood, S., and Sharma, P.D. 2011, Evaluation of Antioxidant and Antiulcer Activity of Traditionally Ocnsumed Cucumis melo Seeds, J. Pharmacol.
Toxicol., 6(1), 82-89
Meda, A.L., Lamien, C.E., Compaoré, M.M.Y., Meda, R.N.T., Kiendrebeogo, M., and Zeba, B., 2008, Polyphenolic Content and Antioxidant Activity of Fourteen Wild Edible Fruits from Burkina Faso,
Molecules, 13, 581-594
Nijveldt, R.J., Nood, E., Hoorn, D.E.C., Boelens, P.G., Norren, K., and Leeuwen, P.A.M., 2001, Flavonoids: a Review of Probable Mechanisms of action and Potential Applications. Am. J. Clin. Nutr.,74, 418-425
Patil, C.B., Mahajan, S.K., and Katti, S.A., 2009, Chalcone: A Versatile Molecule, J. Pharm. Sci & Res.,1(3), 11-22
Phebe, D., Chew, M.K., Suraini, A.A., Lai, O.M., and Janna, O.A., 2009, Redfleshed pitaya (Hylocereus polyrhizus) fruit colour and betacyanin content depend on maturity, Inter. Food Res. J., 16, 233-242
Rebecca, O.P.S., Boyce, A.N., and Chandran, S., 2010, Pigment identification and antioxidant properties of red dragon fruit (Hylocereus polyrhizus), African J. Biotech., 9(10),1450-1454
Sandhar, H.K., Kumar, B., Prasher, S., Tiwari, P., Salhan, M., and Sharma, P., 2011, A Review of Phytochemistry and Pharmacology of Flavonoids, Int Pharm Sci.,1(1), 25-41
Wu, L., Hsu, H., Chen, Y., Chiu, C., Lin, Y., and Ho, J.A., 2006, Antioxidant and antiproliferative Activities of Red Pitaya. Food Chem., 95, 319-327
- There are currently no refbacks.
Copyright (c) 2017 INDONESIAN JOURNAL OF PHARMACY
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
Indonesian J Pharm indexed by:View My Stats