DASYPOGALACTONE, A NEW CHIRALIC C3-SYMMETRIC MACROLACTONE FROM LICHEN USNEA DASYPOGA ROHL.

Ratna Layla Gani, Wahyudi Priyono Suwarso, Karsten Krohn, Markus John

Abstract


Medicinal plants spread out in Indonesia, however only a part of them have been clinically investigated that exhibited therapeutic effecs. This research was to isolate a new compounds in Usnea dasypoga. A new twentyfour-membered macrolactone composed of three units of unknown fatty acid (2R*,3R*,4S*,7S* or 2S* 3S* 4R*, 7R*)-3,7-dihydroxy-2,4-dimethyloctanoic acid forming a C3-symmetrical lactide was isolated from Indonesian lichen Usnea dasypoga Rohl. The result shown that those compound had been confirmed with the spectroscopic data.

Keywords: Natural products isolation, three lactide, lichen


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References


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DOI: http://dx.doi.org/10.14499/indonesianjpharm0iss0pp109-114

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