Characterization antibacterial constituent from Ficus deltoideusJack leaves

Suryati .; Hazli Nurdin; Dachriyanus .; Md Nordin Hj Lajis

doi:10.14499/indonesianjpharm0iss0pp134-138

Characterization antibacterial constituent from Ficus deltoideusJack leaves

Suryati ., Hazli Nurdin, Dachriyanus ., Md Nordin Hj Lajis

Abstract

An antibacterial constituent, has been isolated from Ficus deltoideus Jack leaves. Based on spectroscopic data (IR, 1H-NMR, 13 C NMR 1D and 2D and MS), the structure of this compound was identified as Olean-12en-3β-ol, (β-amyrin), C₃₀H₅₀O. This compound showed antibacterial activities against E. coli, B. subtilis and S. aureus. The minimum inhibition concentration (MIC) agains E. coli, B. subtilisand S. aureusare 230, 380 and 460 (µg/mL) respectively.

Key words: Antibacterial activity,Ficus deltoideusJack, β-amyrin

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DOI: http://dx.doi.org/10.14499/indonesianjpharm0iss0pp134-138