Imaniar Noor Faridah, Venty Dewintasari


Treatment of diabetes mellitus patients can be vary, using monotherapy or combination therapy, and it depends on the severity of the disease from each person. That variation will give influences to the patient’s clinical condition and also their quality of life. The objective of this study is to determine the average of quality of life’s score in diabetes mellitus patients who use monotherapy and combination therapy of antidiabetic oral in Public Health Center of Kotagede 1 Yogyakarta.  

            This study was conducted in a cross sectional  study. Subjects were people who had an age above 18 years old, got the diagnose of diabetes mellitus type 2 and have been attended to the public health center, and also consumed of oral antidiabetic monotherapy or combination. The measurement of quality of life is using a DQLCTQ questionnaire in Bahasa Indonesia version. Analysis statistic with independent sample T-test was used to determine the differences between quality of life in patients who use monotherapy and combination therapy.

            Subjects who met the inclusion criteria are 52 patients. About  82.70% (43 patients) of the patients used oral antidiabetic combination and the other (9 patients) used oral antidiabetic monotherapy. The average of quality of life in monotherapy patients (78.95 + 11.36) was higher than in combination therapy patients (75.18 + 10.57). Result of the analysis statistic showed that there is no significant differences (p 0.095) of quality of life between monotherapy patients and combination therapy patients.


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DOI: http://dx.doi.org/10.14499/indonesianjpharm28iss2pp%25p


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